Confocal laser scanning microscopy CLSM: Convenience comes standard at Rotary House. In patients with extensive LPLs selected parts of the lesion may be removed depending on clinical appearance and localisation. We observe that normal lymphocytes do not show any detectable TK1 on their membrane fraction. Sections from the paraffin embedded biopsies are retrieved and DNA is extracted according to the method described by Jalouli et al. His experience was more typical than that of Padnick.
Thus, analysis of genetic aberrations and immune response may not only facilitate diagnosis but also give rise to new treatment options.
1. Översiktlig projektbeskrivning
Clinical value of thymidine kinase in patients with cervical carcinoma. Diagnosis including degree of dysplasia will also entered the database. While investigating this hypothesis, we found TK1 to be overexpressed on the membrane of BL, acute promyelocytic leukemia, acute T cell leukemia, and ALL clinical samples. The flask was incubated on a rocking platform with gentle agitation for 30 minutes at 4°C. Oral white lesions with special reference to precancerous and tobacco- related lesions: The diluted interface was centrifuged at 47, rpm for 1 hour, and the pellet was resuspended in 1 mL Tris buffer pH 6. TK1 is absent on the plasma membrane of normal lymphocytes To test whether TK1 membrane localization was exclusive to malignant cells, we stained normal resting lymphocytes from whole blood with our antibodies.